Global Gene Therapy Market Highlights Over 2022 - 2031

The global gene therapy market is estimated to garner around USD 6 billion in revenue by 2031 by growing at a CAGR of nearly 34% over the forecast period, i.e., 2022 – 2031. The growth of the market can be attributed to the increasing prevalence of cancer cases, and the ethical acceptance of gene therapy for cancer treatment. For instance, according to the World Cancer Research Fund, cancer cases all over the world were estimated to be 18.1 million in 2020, out of which, 9.3 million cases were in men and 8.8 million in women. Gene therapies are promising therapies applicable to a wide range of diseases, their aim is to radically treat the causes of the diseases instead of only relieving the symptoms.

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Additionally, rising awareness regarding the benefits of using gene therapy as compared to traditional therapy for the treatment of various diseases, and government support to promote gene therapy-related research are also the major factors that are projected to boost the growth of the gene therapy market. 

The COVID-19 had a positive effect on the gene therapy market on the back of extensive utilization of gene technology in the development of vaccines used to treat COVID-19. 

However, high operational costs associated with gene therapy and unwanted immune responses are expected to hamper the growth of the gene therapy market. 

The market is segmented by indication into cancer, metabolic disorders, eye disorders, cardiovascular diseases, and others, out of which, the cancer segment is anticipated to hold the major share over the forecast period. The growth can be attributed to the increasing prevalence of cancer cases. Several types of cancers, such as brain, lung, breast, pancreatic, liver, prostate, bladder, head and neck, skin, and ovarian cancers are treated with the help of gene therapies. For instance, according to the World Cancer Research Fund, the most common cancers worldwide are breast and lung cancers, contributing 12.5% and 12.2%, respectively, of the total number of new cases diagnosed in 2020.  

Global Gene Therapy Market Regional Synopsis

Regionally, the global gene therapy market is segmented into five major regions including North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa region. The market in North America region is estimated to witness significant growth over the forecast period on the back of rapidly growing cancer cases, presence of high disposable income, and increase in funding for R&D activities related with gene therapy. For instance, according to the Cancer Facts & Figures 2021 report, the estimated number of new cancer cases diagnosed in the United States were 1.9 million in 2021.

On the other hand, Asia-Pacific is expected to witness the highest CAGR during the forecast period owing to the rising number of people prone to various chronic diseases, and increasing approval & launch of gene therapy products. Moreover, an increase in a government initiative to improve healthcare infrastructure, and a rise in healthcare expenditure is predicted to also boost the market growth of the region.

Market Segmentation

Our in-depth analysis of the global gene therapy market includes the following segments:

By Indication

• Cancer

• Metabolic Disorders

• Eye Disorders

• Cardiovascular Diseases

• Others

By Technology

• Adeno Virus Vector

• Adeno-associated Virus Vector

• Lentiviral Vector

• Retroviral Vector

• Herpes Virus Vector

• Others

By Application

• Clinical

• Commercial

By End-User

• Pharma & Biotech

• Academia

Growth Drivers and Challenges Impacting the Growth of the Global Gene Therapy Market

Growth Drivers

• Increasing prevalence of cancer cases, and ethical acceptance of gene therapy for cancer treatment

• Rising awareness regarding benefits of using gene therapy as compared to traditional therapy

Challenges

• High operational costs associated with gene therapy

• Unwanted immune responses

Key Companies Dominating the Global Gene Therapy Market

Our report has covered detailed company profiling comprising company overview, business strategies, key product offerings, financial performance, key performance indicators, risk analysis, recent developments, regional presence, and SWOT analysis among other notable indicators for competitive positioning. Some of the prominent industry leaders in the global gene therapy market that are included in our report are Kineta, Inc., Novartis AG, Amgen Inc., bluebird bio, Inc., Gilead Sciences, Inc., Orchard Therapeutics plc, SIBIONO, Questex, CRISPR Therapeutics, Editas Medicine, and others.

Latest Developments in the Global Gene Therapy Market:

• December 2018: Kineta Immuno-Oncology, LLC, a subsidiary of Kineta, Inc., announced its strategic research collaboration and license agreement with Pfizer Inc. to expand RIG-I agonist immunotherapies for the cancer treatment.

• May 2019: AveXis, a subsidiary of Novartis AG, announced the approval of Zolgensma (onasemnogene abeparvovec-xioi) by the U.S. Food and Drug Administration (FDA), to cure pediatric patients younger than 2 years of age with spinal muscular atrophy (SMA) with bi-allelic mutations in the survival motor neuron 1 (SMN1) gene.

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• The report covers detailed analysis comprising market share attained by each market segment and its sub-segments.

• It covers market dynamics including growth drivers, trends, potential opportunities, price trend analysis and challenges that impact the market growth.

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Geography Analysis:

The report further discusses the market opportunity, compound annual growth rate (CAGR) growth rate, competition, new technology innovations, market players analysis, government guidelines, export and import (EXIM) analysis, historical revenues, future forecasts etc. in the following regions and/or countries:

• North America (U.S. & Canada) Market Size, Y-O-Y Growth, Market Players Analysis & Opportunity Outlook
• Latin America (Brazil, Mexico, Argentina, Rest of Latin America) Market Size, Y-O-Y Growth & Market Players Analysis & Opportunity Outlook
• Europe (U.K., Germany, France, Italy, Spain, Hungary, Belgium, Netherlands & Luxembourg, NORDIC(Finland, Sweden, Norway, Denmark), Ireland, Switzerland, Austria, Poland, Turkey, Russia, Rest of Europe), Poland, Turkey, Russia, Rest of Europe) Market Size, Y-O-Y Growth Market Players Analys  & Opportunity Outlook
• Asia-Pacific (China, India, Japan, South Korea, Singapore, Indonesia, Malaysia, Australia, New Zealand, Rest of Asia-Pacific) Market Size, Y-O-Y Growth & Market Players Analysis & Opportunity Outlook
• Middle East and Africa  (Israel, GCC (Saudi Arabia, UAE, Bahrain, Kuwait, Qatar, Oman), North Africa, South Africa, Rest of Middle East and Africa) Market Size, Y-O-Y Growth Market Players Analysis & Opportunity Outlook

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