Hormone Replacement Therapy (HRT) Market, By Replacement Therapy (Estrogen, Human Growth Hormone, Testosterone and Thyroid), By Route of Administration, By Disease, and Geography (NA, EU, APAC, and RoW) – Analysis, Share, Trends, Size, & Forecast From 2014 – 2025

REPORT HIGHLIGHT
The Hormone Replacement Therapy (HRT) market is estimated to represent a global market of USD 15.8 billion by 2017 with growth rate of 7.5%.

Market Dynamics

Menopause is a natural and inevitable event, defined as the final menstrual period. It requires a retrospective clinical diagnosis with ethnic and regional variations. Hormone replacement therapies (HRT) such as systemic estrogen (skin patch, gel, or cream) are considered to be the most effective treatment option in the treatment of menopausal night sweats and hot flashes. These therapies also ease vaginal symptoms of menopause such as itching, burning, and dryness. Due to this fact, women undergoing these therapies has increased considerably over the past few years.

As per the Rose Research Survey (April 2014), women accepting HT therapy has increased considerably, from 4.5 million in 2005 to around 5.0 million in 2014. In addition to this, the growth of this market is attributed to the rise in a number of women in menopausal age coupled with growing patient awareness. For example, according to the International Menopause Society, thousands of women reach menopause experience every day. On another hand, the high cost of therapies coupled with the high risk of adverse reactions posing a potential threat to this industry. For example, as per the study published in PLOS One journal in 2014, testosterone therapy in cardiac patients considerably increase the risk of heart attack.

Replacement Therapy Takeaway

In terms of replacement therapy, the market is categorized as Estrogen, Human Growth Hormone, Testosterone and Thyroid. Estrogen replacement therapy recorded USD 9.58 billion and is expected to soar owing to the approval of new products by the United States Food and Drug Association under this category. Some of the recommended estrogen doses for women with Primary Ovarian Insufficiency (POI) are 1.25 mg conjugated equine estrogen (CEE), 17b-estradiol 2 mg/day, and transdermal estradiol 75–100 mg/day.

Furthermore, Climara, Estradot, Divigel, Elestrin, and EstroGel are some of the commercially available transdermal estrogen products in the U.S. and Canada market by various manufacturers. On contrary, thyroid replacement therapy is considered to be the lowest revenue generating segment and is also pegged to register slowest growth rate i.e. 6.9% in terms of value. Levothyroxine (generic form of thyroxine) is a most commonly prescribed thyroid hormone replacement drug across the globe.

Route of Administration Takeaway

Route of administration is divided into Parenteral, Oral, Transdermal, and other. Among which, the parenteral segment recorded the highest share of the global market owing to its associated benefits. For example, parenteral administration of estrogen protect against the effects of andropause and reduce toxicity compared to the oral administration. The disease segment is divided into Male hypogonadism, Menopause, Hypothyroidism, Growth hormone deficiency, and others. Hypothyroidism is the lowest revenue generating segment, captured less than 15% share throughout the forecast period.

Regional Takeaway

Regionally, the market is divided into North America, Europe, Asia Pacific and Rest of the World. Of these, North America captured the highest share, 41.67% of the total market. Drugs such as Premarin, AndroGel, and Levothyroxine have been recorded to gain the maximum prescription within this region. However, Asia Pacific region represents one of the fastest growing regions, enjoying an annual average growth rate over 9.0%. Rising awareness levels coupled with increasing focus of healthcare and government on eradication of hormonal deficiencies are likely to establish a healthy platform for the industry growth in this region.

Key Vendor Takeaway

Companies such as Novo Nordisk, Amgen, Inc., Abbott, Eli Lily and Genentech are covered under research study. The industry experiences a high level of competition. In such fragmented landscape, key players are actively engaged in strategic collaborations to expand their market presence. For instance, in February 2015, Mylan Laboratories signed an agreement for the acquisition of Famy Care.

This acquisition has helped the company to increase its female health product portfolio inclusive of production of hormone replacement drugs, Intra-Uterine Devices (IUD), and contraceptives. Likewise, in December 2014, Pfizer collaborated with OPKO Health. As per the agreement, OPKO would be developing and marketing long-acting human growth hormone (hGH-CTP) (PF-06836922), whereas Pfizer would take care of the post-market studies and development costs.

The market size and forecast for each segment and sub-segments has been considered as below:

Historical Year – 2014 & 2016
Base Year – 2017
Estimated Year – 2018
Projected Year – 2025
TARGET AUDIENCE

Traders, Distributors, and Suppliers
Manufacturers
Hospitals
Government and Regional Agencies and Research Organizations
Consultants
Distributors
SCOPE OF THE REPORT

The scope of this report covers the market by its major segments, which include as follows:

MARKET, BY REPLACEMENT THERAPY

Estrogen
Human Growth Hormone
Testosterone
Thyroid
MARKET, BY ROUTE OF ADMINISTRATION

Parenteral
Oral
Transdermal
Other
MARKET, BY DISEASE

Male Hypogonadism
Menopause
Hypothyroidism
Growth Hormone Deficiency
Others
MARKET, BY REGION

North America
U.S.
Canada
Europe
Germany
France
Rest of Europe
Asia Pacific
India
China
Rest of APAC
Rest of the World
Middle East and Africa
Latin America

Geography Analysis:

The report further discusses the market opportunity, compound annual growth rate (CAGR) growth rate, competition, new technology innovations, market players analysis, government guidelines, export and import (EXIM) analysis, historical revenues, future forecasts etc. in the following regions and/or countries:

• North America (U.S. & Canada) Market Size, Y-O-Y Growth, Market Players Analysis & Opportunity Outlook
• Latin America (Brazil, Mexico, Argentina, Rest of Latin America) Market Size, Y-O-Y Growth & Market Players Analysis & Opportunity Outlook
• Europe (U.K., Germany, France, Italy, Spain, Hungary, Belgium, Netherlands & Luxembourg, NORDIC(Finland, Sweden, Norway, Denmark), Ireland, Switzerland, Austria, Poland, Turkey, Russia, Rest of Europe), Poland, Turkey, Russia, Rest of Europe) Market Size, Y-O-Y Growth Market Players Analys  & Opportunity Outlook
• Asia-Pacific (China, India, Japan, South Korea, Singapore, Indonesia, Malaysia, Australia, New Zealand, Rest of Asia-Pacific) Market Size, Y-O-Y Growth & Market Players Analysis & Opportunity Outlook
• Middle East and Africa  (Israel, GCC (Saudi Arabia, UAE, Bahrain, Kuwait, Qatar, Oman), North Africa, South Africa, Rest of Middle East and Africa) Market Size, Y-O-Y Growth Market Players Analysis & Opportunity Outlook

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